What is sixth base in dating Free non register video sex chat
This work has been possible thanks to the development of analytical methods with high sensitivity because levels of m A in described genomes are low.
In addition it seems that m A would play a specific role in stem cells and early stages of development, "explains the researcher.
"However, this issue of publishes three papers suggesting that more complex cells called eukaryotes such as the human body cells, also present the sixth DNA base.
These studies suggest that algae, worms and flies possess m A and it acts to regulate the expression of certain genes, thus constituting a new epigenetic mark.
The researchers then examined embryonic stem cells as well as mouse organs and found that both bases can be detected in genomic DNA.
The finding could have important implications for stem cell research, as it could provide researchers with new tools to erase previous methylation patterns to reprogram adult cells.
For decades, scientists have known that DNA consists of four basic units -- adenine, guanine, thymine and cytosine.
Those four bases have been taught in science textbooks and have formed the basis of the growing knowledge regarding how genes code for life.
It is formed by combining four parts: A, C, G and T (adenine, cytosine, guanine and thymine), called bases of DNA combine in thousands of possible sequences to provide the genetic variability that enables the wealth of aspects and functions of living beings.Yet in recent history, scientists have expanded that list from four to six.Now, researchers have discovered the seventh and eighth bases of DNA.In recent years, interest in this fifth DNA base has increased by showing that alterations in the methyl-cytosine contribute to the development of many human diseases, including cancer.
Today, an article published in by Manel Esteller, director of the Epigenetics and Cancer Biology Program of the Bellvitge Biomedical Research Institute (IDIBELL), ICREA researcher and Professor of Genetics at the University of Barcelona, describes the possible existence of a sixth DNA base, the methyl-adenine (m A), which also help determine the epigenome and would therefore be key in the life of the cells.
"Now the challenge we face is to confirm this data and find out whether mammals, including humans, we also have this sixth DNA base, and consider what its role is." Cancer cells have a different DNA methylation pattern from that of healthy cells.